I just stumbled upon a nice mouse tool: Pitaschio
Basically, it allows you to configure mouse action to several functions. For example, you can configure that a wheel click on the title bar of a window minimizes it. Or, if you use the wheel on the title bar the window becomes transparent so you can view what is behind.
Beside this, it can also lock several keys like Caps Lock or the Windows key (good for Crysis :-).